Fibrinogen human
Evicel, TachoSil, VeraSeal (fibrinogen, human) is an unknown pharmaceutical. Fibrinogen, human was first approved as Tachosil on 2004-06-08. It is used to treat afibrinogenemia and hemorrhage in the USA. It has been approved in Europe to treat hemostasis and surgical hemostasis.
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemorrhage | D006470 | MP_0001914 | R58 | 7 | 17 | 13 | 15 | 31 | 76 |
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | 3 | 4 | 3 | 8 | 32 | 47 |
| Hemostatic disorders | D020141 | — | — | 3 | 4 | 3 | 8 | 32 | 47 |
| Afibrinogenemia | D000347 | — | D68.2 | 1 | 6 | 9 | 4 | 9 | 26 |
| Wounds and injuries | D014947 | — | T14.8 | 5 | 7 | 2 | 2 | 10 | 22 |
| Thrombosis | D013927 | — | — | — | — | 1 | 3 | 10 | 14 |
| Surgical blood loss | D016063 | — | — | — | 2 | 4 | 1 | 7 | 14 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 3 | 2 | 1 | 6 | 12 |
| Postpartum hemorrhage | D006473 | — | O72 | 1 | 2 | 1 | 2 | 4 | 8 |
| Hemostasis | D006487 | — | — | 1 | 2 | 1 | 2 | 2 | 7 |
Show 39 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 2 | 5 | — | 1 | 8 |
| Inflammation | D007249 | MP_0001845 | — | — | — | 1 | — | 7 | 8 |
| Ischemia | D007511 | EFO_0000556 | — | — | 2 | 5 | — | 1 | 8 |
| Ischemic stroke | D000083242 | — | — | — | 2 | 5 | — | — | 7 |
| Coronary artery disease | D003324 | — | I25.1 | — | 2 | 1 | — | 4 | 7 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | 1 | 1 | — | 4 | 6 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | 1 | — | 4 | 5 |
| Postoperative hemorrhage | D019106 | — | — | — | 1 | 1 | — | 3 | 5 |
| Ulcer | D014456 | MPATH_579 | — | — | 1 | 3 | — | 1 | 5 |
| Acromegaly | D000172 | — | — | — | — | 1 | — | 3 | 4 |
Show 30 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | 1 | 1 | — | — | 15 | 17 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | — | 3 | 4 |
| Multiple trauma | D009104 | — | T07 | 1 | 1 | — | — | 3 | 4 |
| Aortic dissection | D000784 | — | I71.0 | — | 1 | — | — | 3 | 4 |
| Pituitary dwarfism | D004393 | EFO_1001109 | E23.0 | — | 1 | — | — | 2 | 3 |
| Dwarfism | D004392 | — | E34.31 | — | 1 | — | — | 2 | 3 |
| Hyperinsulinism | D006946 | — | E16.1 | — | 1 | — | — | 2 | 3 |
| Transfusion reaction | D065227 | — | D69.51 | — | 1 | — | — | 2 | 3 |
| Atrophy | D001284 | — | — | — | 1 | — | — | 2 | 3 |
| Gallstones | D042882 | EFO_0004210 | — | — | 1 | — | — | 1 | 2 |
Show 24 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 4 | — | — | — | 1 | 5 |
| Neutropenia | D009503 | — | D70 | 3 | — | — | — | — | 3 |
| Chemotherapy-induced febrile neutropenia | D064146 | — | — | 3 | — | — | — | — | 3 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 1 | — | — | — | 1 | 2 |
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | 1 | — | — | — | 1 | 2 |
| Gastrointestinal hemorrhage | D006471 | — | K92.2 | 1 | — | — | — | — | 1 |
| Glioma | D005910 | EFO_0000520 | — | 1 | — | — | — | — | 1 |
| Brain stem neoplasms | D020295 | EFO_1001767 | — | 1 | — | — | — | — | 1 |
| Pinealoma | D010871 | — | — | 1 | — | — | — | — | 1 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Embolism | D004617 | — | — | — | — | — | — | 6 | 6 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 6 | 6 |
| Fibrosis | D005355 | — | — | — | — | — | — | 6 | 6 |
| Coagulation protein disorders | D020147 | — | — | — | — | — | — | 5 | 5 |
| Pulmonary embolism | D011655 | EFO_0003827 | I26 | — | — | — | — | 5 | 5 |
| Burns | D002056 | — | T30.0 | — | — | — | — | 4 | 4 |
| Venous thromboembolism | D054556 | EFO_0004286 | I74 | — | — | — | — | 4 | 4 |
| Liver transplantation | D016031 | EFO_0010682 | — | — | — | — | — | 4 | 4 |
| Coronary disease | D003327 | — | — | — | — | — | — | 4 | 4 |
| Leukemia | D007938 | — | C95 | — | — | — | — | 4 | 4 |
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Drug
General
| Drug common name | Fibrinogen human |
| INN | — |
| Description | Evicel, TachoSil, VeraSeal (fibrinogen, human) is an unknown pharmaceutical. Fibrinogen, human was first approved as Tachosil on 2004-06-08. It is used to treat afibrinogenemia and hemorrhage in the USA. It has been approved in Europe to treat hemostasis and surgical hemostasis. |
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109072 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
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